RAP1GAP anticorps (AA 412-660)

N° du produit ABIN5542476

Détail du produit anti-RAP1GAP anticorps

Antigène: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Épitope: AA 412-660

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAP1GAP est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: RAP1GAP Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human RAP1GAP (AA: 412-660) expressed in E. Coli.

Clone: 2G7B6

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur RAP1GAP

Antigène: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Autre désignation: RAP1GAP (RAP1GAP Produits)

Synonymes: anticorps RAP1GA1, anticorps RAP1GAP1, anticorps RAP1GAPII, anticorps RAPGAP, anticorps 1300019I11Rik, anticorps 2310004O14Rik, anticorps AI427470, anticorps Rap1ga1, anticorps RAP1, anticorps RAP1GAP, anticorps rap1ga1, anticorps rap1gap1, anticorps rap1gapii, anticorps rapgap, anticorps zgc:175180, anticorps DKFZp459A114, anticorps RAP1 GTPase activating protein, anticorps Rap1 GTPase-activating protein, anticorps RAP1 GTPase activating protein 1, anticorps RAP1 GTPase activating protein L homeolog, anticorps Rap1 GTPase-activating protein 1, anticorps si:dkey-166d12.2, anticorps RAP1GAP, anticorps Rap1gap, anticorps RAP1GAP1, anticorps rap1gap.L, anticorps Tsp_09520, anticorps rap1gap, anticorps si:dkey-166d12.2

Sujet:

Description: This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Aliases: RAPGAP, RAP1GA1, RAP1GAP1, RAP1GAPII

Poids moléculaire: 73.4kDa

ID gène: 5909

HGNC: 5909

UniProt: P47736