DDX3X anticorps (AA 518-661)

N° du produit ABIN5542508

Détail du produit anti-DDX3X anticorps

Antigène: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Épitope: AA 518-661

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DDX3X est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: DDX3X Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DDX3X (AA: 518-661) expressed in E. Coli.

Clone: 3B9E3

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DDX3X

Antigène: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Autre désignation: DDX3X (DDX3X Produits)

Synonymes: anticorps DBX, anticorps DDX14, anticorps DDX3, anticorps HLP2, anticorps D1Pas1-rs2, anticorps Ddx3, anticorps Fin14, anticorps An3, anticorps pl10, anticorps DDX3X, anticorps DEAD-box helicase 3, X-linked, anticorps DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked, anticorps DEAD-box helicase 3, X-linked L homeolog, anticorps DDX3X, anticorps Ddx3x, anticorps ddx3x.L, anticorps ddx3x

Sujet:

Description: The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.

Aliases: DBX, DDX3, HLP2, DDX14, CAP-Rf

Poids moléculaire: 73.2kDa

ID gène: 1654

HGNC: 1654

UniProt: O00571

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly