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DNMT3L anticorps (AA 147-386)

TRDMT1 Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 2D10H11 unconjugated
N° du produit ABIN5542515
  • Antigène Voir toutes DNMT3L (TRDMT1) Anticorps
    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
    Épitope
    • 15
    • 10
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-386
    Reactivité
    • 72
    • 17
    • 2
    • 1
    Humain
    Hôte
    • 72
    • 5
    Souris
    Clonalité
    • 74
    • 3
    Monoclonal
    Conjugué
    • 33
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DNMT3L est non-conjugé
    Application
    • 64
    • 37
    • 15
    • 13
    • 13
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Fonction
    DNMT3L Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human DNMT3L (AA: 147-386) expressed in E. Coli.
    Clone
    2D10H11
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
    Autre désignation
    DNMT3L (TRDMT1 Produits)
    Synonymes
    anticorps DNMT3L, anticorps D6Ertd14e, anticorps ecat7, anticorps DNA methyltransferase 3 like, anticorps DNA (cytosine-5-)-methyltransferase 3-like, anticorps DNMT3L, anticorps Dnmt3l
    Sujet
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    43.6kDa
    ID gène
    29947
    HGNC
    29947
    UniProt
    Q9UJW3
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