DNMT3B anticorps (AA 1-150)

N° du produit ABIN5542517

Détail du produit anti-DNMT3B anticorps

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Épitope: AA 1-150

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DNMT3B est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Fonction: DNMT3B Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. Coli.

Clone: 4D1A2E5

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DNMT3B

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Autre désignation: DNMT3B (DNMT3B Produits)

Synonymes: anticorps DNMT3B, anticorps LOC100218113, anticorps ICF, anticorps ICF1, anticorps M.HsaIIIB, anticorps MmuIIIB, anticorps cb91, anticorps dnmt3bl, anticorps dnmt7, anticorps sb:cb91, anticorps wu:fb16h07, anticorps DNA methyltransferase 3 beta, anticorps DNA methyltransferase 3B, anticorps DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a, anticorps DNMT3B, anticorps Dnmt3b, anticorps dnmt3b, anticorps dnmt3ba

Sujet:

Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Aliases: ICF, ICF1, M.HsaIIIB

Poids moléculaire: 95.8kDa

ID gène: 1789

HGNC: 1789

UniProt: Q9UBC3