DNMT3B anticorps (AA 1-150)
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- Antigène Voir toutes DNMT3B Anticorps
- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
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Épitope
- AA 1-150
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DNMT3B est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Fonction
- DNMT3B Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. Coli.
- Clone
- 4D1A2E5
- Isotype
- IgG2a
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
- Autre désignation
- DNMT3B (DNMT3B Produits)
- Sujet
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Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
Aliases: ICF, ICF1, M.HsaIIIB
- Poids moléculaire
- 95.8kDa
- ID gène
- 1789
- HGNC
- 1789
- UniProt
- Q9UBC3
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