DNMT3B anticorps (AA 1-150)
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- Antigène Voir toutes DNMT3B Anticorps
- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
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Épitope
- AA 1-150
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DNMT3B est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. coli.
- Clone
- 4D1A2E5
- Isotype
- IgG2a
- Top Product
- Discover our top product DNMT3B Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
- Autre désignation
- DNMT3B (DNMT3B Produits)
- Synonymes
- anticorps DNMT3B, anticorps LOC100218113, anticorps ICF, anticorps ICF1, anticorps M.HsaIIIB, anticorps MmuIIIB, anticorps cb91, anticorps dnmt3bl, anticorps dnmt7, anticorps sb:cb91, anticorps wu:fb16h07, anticorps DNA methyltransferase 3 beta, anticorps DNA methyltransferase 3B, anticorps DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a, anticorps DNMT3B, anticorps Dnmt3b, anticorps dnmt3b, anticorps dnmt3ba
- Sujet
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Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.,
Aliases: ICF, ICF1, M.HsaIIIB
- Poids moléculaire
- 95.8 kDa
- ID gène
- 1789
- HGNC
- 1789
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