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DNMT3B anticorps (AA 1-150)

DNMT3B Reactivité: Humain ELISA, FACS, ICC Hôte: Souris Monoclonal 4D1A2E5 unconjugated
N° du produit ABIN5542517
  • Antigène Voir toutes DNMT3B Anticorps
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    Épitope
    • 17
    • 16
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-150
    Reactivité
    • 84
    • 53
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 81
    • 5
    • 2
    • 1
    Souris
    Clonalité
    • 75
    • 14
    Monoclonal
    Conjugué
    • 34
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DNMT3B est non-conjugé
    Application
    • 71
    • 35
    • 22
    • 21
    • 13
    • 12
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Fonction
    DNMT3B Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. Coli.
    Clone
    4D1A2E5
    Isotype
    IgG2a
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    Autre désignation
    DNMT3B (DNMT3B Produits)
    Sujet

    Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

    Aliases: ICF, ICF1, M.HsaIIIB

    Poids moléculaire
    95.8kDa
    ID gène
    1789
    HGNC
    1789
    UniProt
    Q9UBC3
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