LEF1 anticorps (AA 33-138)
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- Antigène Voir toutes LEF1 Anticorps
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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Épitope
- AA 33-138
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LEF1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Fonction
- LEF1 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human LEF1 (AA: 33-138) expressed in E. Coli.
- Clone
- 1A4B11
- Isotype
- IgG1
- Top Product
- Discover our top product LEF1 Anticorps primaire
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
- Autre désignation
- LEF1 (LEF1 Produits)
- Synonymes
- anticorps LEF1, anticorps 3000002B05, anticorps AI451430, anticorps Lef-1, anticorps LEF-1, anticorps TCF10, anticorps TCF1ALPHA, anticorps TCF7L3, anticorps lymphoid enhancer binding factor 1, anticorps lymphoid enhancer-binding factor 1, anticorps lymphoid enhancer factor XLEF-1B, anticorps LEF1, anticorps lef1, anticorps Lef1
- Sujet
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Description: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Aliases: LEF-1, TCF10, TCF7L3, TCF1ALPHA
- Poids moléculaire
- 44.2kDa
- ID gène
- 51176
- HGNC
- 51176
- UniProt
- Q9UJU2
- Pathways
- Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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