NOTCH3 anticorps (AA 47-156)

N° du produit ABIN5542533

Détail du produit anti-NOTCH3 anticorps

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Épitope: AA 47-156

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOTCH3 est non-conjugé

Application: ELISA

Fonction: Notch3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.

Clone: 2E4D11

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur NOTCH3

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Autre désignation: Notch3 (NOTCH3 Produits)

Synonymes: anticorps CADASIL, anticorps CASIL, anticorps IMF2, anticorps AW229011, anticorps N3, anticorps hpbk, anticorps fa14b08, anticorps notch5, anticorps wu:fa14b08, anticorps notch 3, anticorps NOTCH3, anticorps Notch3, anticorps notch3

Sujet:

Description: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Aliases: IMF2, CASIL, CADASIL

Poids moléculaire: 243.6kDa

ID gène: 4854

HGNC: 4854

UniProt: Q9UM47

Pathways: Signalisation Notch