NOTCH3 anticorps (AA 47-156)
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- Antigène Voir toutes NOTCH3 Anticorps
- NOTCH3 (Notch 3 (NOTCH3))
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Épitope
- AA 47-156
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NOTCH3 est non-conjugé
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Application
- ELISA
- Fonction
- Notch3 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.
- Clone
- 3E2D9
- Isotype
- IgG2a
- Top Product
- Discover our top product NOTCH3 Anticorps primaire
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- NOTCH3 (Notch 3 (NOTCH3))
- Autre désignation
- Notch3 (NOTCH3 Produits)
- Synonymes
- anticorps CADASIL, anticorps CASIL, anticorps IMF2, anticorps AW229011, anticorps N3, anticorps hpbk, anticorps fa14b08, anticorps notch5, anticorps wu:fa14b08, anticorps notch 3, anticorps NOTCH3, anticorps Notch3, anticorps notch3
- Sujet
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Description: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Aliases: IMF2, CASIL, CADASIL
- Poids moléculaire
- 243.6kDa
- ID gène
- 4854
- HGNC
- 4854
- UniProt
- Q9UM47
- Pathways
- Signalisation Notch
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