PPARA anticorps (AA 1-120)

N° du produit ABIN5542540

Détail du produit anti-PPARA anticorps

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Épitope: AA 1-120

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPARA est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Fonction: PPARA Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PPARA (AA: 1-120) expressed in E. Coli.

Clone: 5D10C3

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PPARA

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Autre désignation: PPARA (PPARA Produits)

Synonymes: anticorps NR1C1, anticorps PPAR, anticorps PPARalpha, anticorps hPPAR, anticorps LOC100136415, anticorps PPARALPHA, anticorps nr1c1, anticorps xPPARalpha, anticorps xppara, anticorps 4933429D07Rik, anticorps AW742785, anticorps Nr1c1, anticorps PPAR-alpha, anticorps Ppar, anticorps peroxisome proliferator activated receptor alpha, anticorps peroxisome proliferator-activated receptor alpha, anticorps peroxisome proliferator activated receptor alpha L homeolog, anticorps PPARA, anticorps LOC100136415, anticorps ppara.L, anticorps Ppara, anticorps ppara

Sujet:

Description: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Aliases: PPAR, NR1C1, hPPAR, PPARalpha

Poids moléculaire: 52.2kDa

ID gène: 5465

HGNC: 5465

UniProt: Q07869

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C