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TCL1A anticorps (AA 10-104)

TCL1A Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 2E3A5 unconjugated
N° du produit ABIN5542543
  • Antigène Voir toutes TCL1A Anticorps
    TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
    Épitope
    • 10
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 10-104
    Reactivité
    • 42
    • 2
    • 1
    Humain
    Hôte
    • 28
    • 14
    • 1
    Souris
    Clonalité
    • 29
    • 14
    Monoclonal
    Conjugué
    • 26
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TCL1A est non-conjugé
    Application
    • 17
    • 14
    • 9
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Fonction
    TCL1A Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.
    Clone
    2E3A5
    Isotype
    IgG1
    Top Product
    Discover our top product TCL1A Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
    Autre désignation
    TCL1A (TCL1A Produits)
    Synonymes
    anticorps TCL1A, anticorps Tcl1a, anticorps TCL1, anticorps Tcl1, anticorps T-cell leukemia/lymphoma 1A, anticorps T cell lymphoma breakpoint 1, anticorps TCL1A, anticorps Tcl1, anticorps Tcl1a
    Sujet

    Description: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).

    Aliases: TCL1

    Poids moléculaire
    13.5kDa
    ID gène
    8115
    HGNC
    8115
    UniProt
    P56279
    Pathways
    Stem Cell Maintenance
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