TCL1A anticorps (AA 10-104)
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- Antigène Voir toutes TCL1A Anticorps
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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Épitope
- AA 10-104
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TCL1A est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS)
- Fonction
- TCL1A Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.
- Clone
- 2E3A5
- Isotype
- IgG1
- Top Product
- Discover our top product TCL1A Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Autre désignation
- TCL1A (TCL1A Produits)
- Synonymes
- anticorps TCL1A, anticorps Tcl1a, anticorps TCL1, anticorps Tcl1, anticorps T-cell leukemia/lymphoma 1A, anticorps T cell lymphoma breakpoint 1, anticorps TCL1A, anticorps Tcl1, anticorps Tcl1a
- Sujet
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Description: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
Aliases: TCL1
- Poids moléculaire
- 13.5kDa
- ID gène
- 8115
- HGNC
- 8115
- UniProt
- P56279
- Pathways
- Stem Cell Maintenance
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