p130 anticorps (AA 939-1139)
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- Antigène Voir toutes p130 (RBL2) Anticorps
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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Épitope
- AA 939-1139
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp p130 est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS)
- Fonction
- RBL2 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human RBL2 (AA: 939-1139) expressed in E. Coli.
- Clone
- 2C8A8
- Isotype
- IgG1
- Top Product
- Discover our top product RBL2 Anticorps primaire
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anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 165-194), (N-Term) antibody
RBL2 Reactivité: Humain WB, FACS Hôte: Lapin Polyclonal RB31021 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 26-367) antibodyRBL2 Reactivité: Humain, Rat, Souris, Blow Fly, Poulet WB, IF, IHC, IP Hôte: Souris Monoclonal 10-Rb2 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reactivité: Rat, Souris IF, IHC Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 100-200) antibodyRBL2 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 878-913) antibodyRBL2 Reactivité: Humain, Rat WB, IF, IHC, IHC (p), IP Hôte: Souris Monoclonal 130P215 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 417-616) antibodyRBL2 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reactivité: Humain, Rat, Souris WB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reactivité: Humain, Rat, Souris ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 416-515) antibodyRBL2 Reactivité: Humain ELISA, WB Hôte: Souris Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reactivité: Humain, Chimpanzé ELISA, WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
- Autre désignation
- RBL2 (RBL2 Produits)
- Synonymes
- anticorps RBL2, anticorps RBR2, anticorps RRB2a, anticorps PRB2, anticorps RBR-2, anticorps Rb2, anticorps p130, anticorps P130, anticorps retinoblastoma-like 2 (p130), anticorps RB transcriptional corepressor like 2, anticorps related to retinoblastoma 2, anticorps RBL2, anticorps LOC541652, anticorps Rbl2
- Sujet
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Description: RBL2 is a Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Aliases: Rb2, P130
- Poids moléculaire
- 128.4kDa
- ID gène
- 5934
- HGNC
- 5934
- UniProt
- Q08999
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases
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