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PYCARD anticorps (AA 1-120)

PYCARD Reactivité: Humain WB, ELISA, IHC, FACS, ICC Hôte: Souris Monoclonal 1C3D3 unconjugated
N° du produit ABIN5542580
  • Antigène Voir toutes PYCARD Anticorps
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Épitope
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-120
    Reactivité
    • 56
    • 10
    • 9
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 48
    • 6
    • 3
    Souris
    Clonalité
    • 47
    • 10
    Monoclonal
    Conjugué
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PYCARD est non-conjugé
    Application
    • 39
    • 22
    • 14
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human PYCARD (AA: 1-120) expressed in E. coli.
    Clone
    1C3D3
    Isotype
    IgG1
    Top Product
    Discover our top product PYCARD Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Autre désignation
    PYCARD (PYCARD Produits)
    Synonymes
    anticorps ASC, anticorps CARD5, anticorps TMS, anticorps TMS-1, anticorps TMS1, anticorps 9130417A21Rik, anticorps Asc, anticorps TNS1, anticorps masc, anticorps asc1, anticorps zAsc, anticorps zgc:109874, anticorps PYD and CARD domain containing, anticorps PYCARD, anticorps Pycard, anticorps pycard
    Sujet

    Description: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.,

    Aliases: ASC, TMS, TMS1, CARD5, TMS-1

    Poids moléculaire
    21.6 kDa
    ID gène
    29108
    HGNC
    29108
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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