MMP14 anticorps (AA 112-246)
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- Antigène Voir toutes MMP14 Anticorps
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
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Épitope
- AA 112-246
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MMP14 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Fonction
- MMP14 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human MMP14 (AA: 112-246) expressed in E. Coli.
- Clone
- 6A11D1
- Isotype
- IgG1
- Top Product
- Discover our top product MMP14 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
- Autre désignation
- MMP14 (MMP14 Produits)
- Sujet
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Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Aliases: MMP-14, MMP-X1, MT-MMP, MT1MMP, MTMMP1, WNCHRS, MT1-MMP, MT-MMP 1
- Poids moléculaire
- 65.9kDa
- ID gène
- 4323
- HGNC
- 4323
- UniProt
- P50281
- Pathways
- Autophagy
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