SSH1 anticorps (AA 1032-1044)

N° du produit ABIN5542668

Détail du produit anti-SSH1 anticorps

Antigène: SSH1 (Slingshot Homolog 1 (SSH1))

Épitope: AA 1032-1044

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SSH1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Fonction: SLINGSHOT-1L Antibody

Purification: Purified antibody

Immunogène: Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.

Clone: 6C11G9

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur SSH1

Antigène: SSH1 (Slingshot Homolog 1 (SSH1))

Autre désignation: SLINGSHOT-1L (SSH1 Produits)

Synonymes: anticorps AW551225, anticorps Gm1394, anticorps Gm1395, anticorps SSH-1, anticorps mSSH-1L, anticorps SSH1L, anticorps slingshot homolog 1 (Drosophila), anticorps slingshot protein phosphatase 1, anticorps Ssh1, anticorps SSH1

Sujet:

Description: The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Aliases: SSH1,SSH1L

Poids moléculaire: 115.5kDa

ID gène: 54434

HGNC: 54434

UniProt: Q8WYL5

Pathways: CXCR4-mediated Signaling Events