RAD50 anticorps (AA 228-359)

N° du produit ABIN5542671

Détail du produit anti-RAD50 anticorps

Antigène: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Épitope: AA 228-359

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAD50 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human RAD50 (AA: 228-359) expressed in E. coli.

Clone: 3D2G10

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: , FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur RAD50

Antigène: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Autre désignation: RAD50 (RAD50 Produits)

Synonymes: anticorps NBSLD, anticorps RAD502, anticorps hRad50, anticorps Mrell, anticorps Rad50l, anticorps 6339, anticorps CG6339, anticorps Dmel\\CG6339, anticorps Dmrad50, anticorps RAD50, anticorps Rad50, anticorps ATRAD50, anticorps DNA REPAIR-RECOMBINATION PROTEIN, anticorps F22D22.28, anticorps F22D22_28, anticorps SPAP4C9.01c, anticorps im:6906849, anticorps si:ch211-79h18.3, anticorps RAD50 double strand break repair protein, anticorps CG6339 gene product from transcript CG6339-RE, anticorps RAD50 homolog, double strand break repair protein L homeolog, anticorps rad50, anticorps DNA repair protein RAD50, anticorps RAD50 homolog, double strand break repair protein, anticorps DNA repair-recombination protein (RAD50), anticorps MRX complex DNA-binding subunit, anticorps DNA repair protein Rad50, anticorps RAD50 recombination protein, anticorps Rad50 DNA repair/recombination protein, anticorps DNA repair protein rad-50, anticorps RAD50, anticorps Rad50, anticorps rad50, anticorps rad50.L, anticorps LOC658288, anticorps LOC726642, anticorps rad-50

Sujet:

Description: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.,

Aliases: NBSLD, RAD502, hRad50

Poids moléculaire: 154 kDa

ID gène: 10111

HGNC: 10111

Pathways: Réparation de l'ADN, Protein targeting to Nucleus