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Phospholipase C gamma 1 anticorps (AA 39-181)

PLCG1 Reactivité: Humain WB, ELISA, IHC, ICC, FACS Hôte: Souris Monoclonal 2F3E10 unconjugated
N° du produit ABIN5542683
  • Antigène Voir toutes Phospholipase C gamma 1 (PLCG1) Anticorps
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Épitope
    • 36
    • 28
    • 13
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-181
    Reactivité
    • 144
    • 136
    • 126
    • 22
    • 10
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 149
    • 27
    Souris
    Clonalité
    • 141
    • 35
    Monoclonal
    Conjugué
    • 79
    • 11
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Cet anticorp Phospholipase C gamma 1 est non-conjugé
    Application
    • 117
    • 52
    • 38
    • 30
    • 27
    • 21
    • 20
    • 16
    • 11
    • 11
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human PLCG1 (AA: 39-181) expressed in E. coli.
    Clone
    2F3E10
    Isotype
    IgG2a
    Top Product
    Discover our top product PLCG1 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Autre désignation
    PLCG1 (PLCG1 Produits)
    Synonymes
    anticorps NCKAP3, anticorps PLC-II, anticorps PLC1, anticorps PLC148, anticorps PLCgamma1, anticorps plc1, anticorps nckap3, anticorps plc-ii, anticorps plc148, anticorps plcgamma1, anticorps PPLCA, anticorps AI894140, anticorps Cded, anticorps Plc-1, anticorps Plc-gamma1, anticorps Plcg-1, anticorps fj46f04, anticorps wu:fj46f04, anticorps wu:fj57a05, anticorps phospholipase C gamma 1, anticorps phospholipase C gamma 1 L homeolog, anticorps 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, anticorps phospholipase C, gamma 1, anticorps PLCG1, anticorps plcg1.L, anticorps LOC100633163, anticorps Plcg1, anticorps plcg1
    Sujet

    Description: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.,

    Aliases: PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1

    Poids moléculaire
    148.5 kDa
    ID gène
    5335
    HGNC
    5335
    Pathways
    Signalisation RTK, Signalisation WNT, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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