Cyclin D3 anticorps
-
- Antigène Voir toutes Cyclin D3 (CCND3) Anticorps
- Cyclin D3 (CCND3)
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp Cyclin D3 est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant human Cyclin D3 protein, around C-terminal 200aa.
- Clone
- 4A8
- Isotype
- IgG
- Top Product
- Discover our top product CCND3 Anticorps primaire
-
-
- Indications d'application
-
WB 1:300-5000
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- Cyclin D3 (CCND3)
- Autre désignation
- Cyclin D3 (CCND3 Produits)
- Synonymes
- anticorps zgc:103502, anticorps CCND3, anticorps 9230106B05Rik, anticorps AA682053, anticorps AL024085, anticorps AW146355, anticorps C78795, anticorps cyclin D3, anticorps ccnd3, anticorps CCND3, anticorps Ccnd3
- Sujet
-
Synonyms: G1/S-specific cyclin-D3, CCND3
Background: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
- ID gène
- 896
- UniProt
- P30281
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
-