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Cyclin E1 anticorps (pThr77)

CCNE1 Reactivité: Humain WB, IF (cc) Hôte: Lapin Monoclonal 4G10 unconjugated
N° du produit ABIN5557296
  • Antigène Voir toutes Cyclin E1 (CCNE1) Anticorps
    Cyclin E1 (CCNE1)
    Épitope
    • 26
    • 16
    • 16
    • 13
    • 9
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr77
    Reactivité
    • 146
    • 36
    • 33
    • 3
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 120
    • 25
    • 1
    Lapin
    Clonalité
    • 115
    • 31
    Monoclonal
    Conjugué
    • 81
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Cyclin E1 est non-conjugé
    Application
    • 98
    • 49
    • 48
    • 43
    • 32
    • 27
    • 20
    • 13
    • 12
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    Synthetic peptide derived from human Cyclin E1(T77), around 50-100aa (phospho T77).
    Clone
    4G10
    Isotype
    IgG
    Top Product
    Discover our top product CCNE1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Cyclin E1 (CCNE1)
    Autre désignation
    Cyclin E1 (CCNE1 Produits)
    Synonymes
    anticorps CCNE1, anticorps ccne, anticorps cyclinE, anticorps CCNE, anticorps AW538188, anticorps CycE1, anticorps CYCLE, anticorps Ccne, anticorps cyce2, anticorps cycE3, anticorps cyce, anticorps fa18e07, anticorps wu:fa18e07, anticorps cyclin E1, anticorps cyclin E1 L homeolog, anticorps cyclin E1 S homeolog, anticorps CCNE1, anticorps ccne1, anticorps Ccne1, anticorps ccne1.L, anticorps ccne1.S
    Sujet

    Synonyms: Cyclin E1 phospho T77, p-Cyclin E1 phospho T77, Cyclin E1 Thr77, CCNE 1, CCNE,CCNE1,Cyclin E1 antibody Cyclin Es,Cyclin Et,CyclinE, G1/S specic cyclin E.

    Background: Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

    ID gène
    898
    UniProt
    P24864
    Pathways
    Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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