Histone H3.3 anticorps

N° du produit ABIN5557308

Détail du produit anti-Histone H3.3 anticorps

Antigène: Histone H3.3

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H3.3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant human Histone H3.3 protein, full length.

Clone: 7B12

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Histone H3.3

Antigène: Histone H3.3

Abstract: Histone H3.3 Produits

Synonymes: anticorps H3.3A, anticorps H3F3, anticorps H3-IX, anticorps H3-X, anticorps H3.3B, anticorps H3F3C, anticorps H3F3B, anticorps H3 histone family member 3A, anticorps H3 histone, family 3A, anticorps H3 histone, family 3B, anticorps H3 histone, family 3C L homeolog, anticorps histone H3.3, anticorps Histone H3.3, anticorps histone H3.3B-like, anticorps H3F3A, anticorps H3F3B, anticorps H3f3a, anticorps h3f3c.L, anticorps LOC5567559, anticorps Bm1_29875, anticorps Bm1_40030, anticorps PTRG_03457, anticorps Phum_PHUM492720, anticorps UREG_07214, anticorps PAAG_07099, anticorps PITG_06950, anticorps PITG_06953, anticorps PITG_06955, anticorps LOC100361558, anticorps LOC100521680

Sujet:

Synonyms: H3F3, H3.3A, Histone H3.3, H3F3A, PP781

Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

ID gène: 3020

UniProt: P84243