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SIRT1 anticorps (pThr530)

SIRT1 Reactivité: Humain IF (cc), IHC (p) Hôte: Lapin Monoclonal 6H5 unconjugated
N° du produit ABIN5557342
  • Antigène Voir toutes SIRT1 Anticorps
    SIRT1 (Sirtuin 1 (SIRT1))
    Épitope
    • 31
    • 16
    • 16
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr530
    Reactivité
    • 145
    • 88
    • 60
    • 34
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 129
    • 20
    • 2
    • 2
    • 1
    Lapin
    Clonalité
    • 118
    • 36
    Monoclonal
    Conjugué
    • 64
    • 13
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Cet anticorp SIRT1 est non-conjugé
    Application
    • 116
    • 50
    • 47
    • 40
    • 39
    • 35
    • 22
    • 22
    • 16
    • 13
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    Synthetic peptide derived from human SIRT1(T530), around 500-550aa (phospho T530).
    Clone
    6H5
    Isotype
    IgG
    Top Product
    Discover our top product SIRT1 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SIRT1 (Sirtuin 1 (SIRT1))
    Autre désignation
    SIRT1 (SIRT1 Produits)
    Synonymes
    anticorps sirtuin 1, anticorps AA673258, anticorps SIR2L1, anticorps Sir2, anticorps Sir2a, anticorps Sir2alpha, anticorps sir2l1, anticorps sirtuin, anticorps SIR2, anticorps sirtuin 1, anticorps sirtuin 1 L homeolog, anticorps SIRT1, anticorps SRT1, anticorps Sirt1, anticorps sirt1.L
    Sujet

    Synonyms: SIR2L1, NAD-dependent protein deacetylase sirtuin-1, hSIRT1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SIRT1

    Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

    ID gène
    23411
    UniProt
    Q96EB6
    Pathways
    Signalisation MAPK, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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