Recombinant Netrin 1 anticorps
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- Antigène Voir toutes Netrin 1 (NTN1) Anticorps
- Netrin 1 (NTN1)
- Type d'anticorp
- Recombinant Antibody
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Reactivité
- Humain, Souris
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Hôte
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Human
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Netrin 1 est non-conjugé
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Application
- ELISA, Functional Studies (Func)
- Specificité
- Recognizes human and mouse Netrin-1.
- Réactivité croisée
- Humain, Souris
- Réactivité croisée (Details)
- Does not recognize Netrin-4.
- Pureté
- >95 % (SDS-PAGE)
- Immunogène
- Recombinant human netrin-1.
- Clone
- H4
- Isotype
- IgG2
- Top Product
- Discover our top product NTN1 Anticorps primaire
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- Commentaires
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anti-Netrin-1 (human), mAb (rec.) (blocking) (H4) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol.
- Agent conservateur
- Without preservative
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Date de péremption
- 12 months
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- Antigène
- Netrin 1 (NTN1)
- Autre désignation
- Netrin-1 (NTN1 Produits)
- Synonymes
- anticorps ntn1-A, anticorps Netrin-1, anticorps NTN1, anticorps unc-6, anticorps MGC147073, anticorps NTN1L, anticorps AI561871, anticorps BC019633, anticorps netrin-1, anticorps netrin 1 L homeolog, anticorps netrin 1, anticorps ntn1.L, anticorps NTN1, anticorps ntn1, anticorps Ntn1
- Sujet
- Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.
- UniProt
- O95631
- Pathways
- Regulation of Cell Size
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