Huntingtin anticorps (Internal Region, pSer1201)
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- Antigène Voir toutes Huntingtin (HTT) Anticorps
- Huntingtin (HTT)
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Épitope
- Internal Region, pSer1201
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Huntingtin est non-conjugé
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Application
- ELISA, Western Blotting (WB)
- Réactivité croisée (Details)
- A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with Huntington pS1201 from other sources has not been determined.
- Purification
- Anti-Huntington pS1201 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of the S1201 residue.
- Immunogène
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Immunogen: Anti-Huntington pS1201 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human Huntingtin protein.
Immunogen Type: Peptide
- Isotype
- IgG
- Top Product
- Discover our top product HTT Anticorps primaire
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- Indications d'application
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Application Note: Anti-HTT antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~350 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1: 10,000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.08 mg/mL
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol with 1 mg/mL Bovine Serum Albumin (BSA)
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Date de péremption
- 12 months
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- Antigène
- Huntingtin (HTT)
- Autre désignation
- Huntington (HTT Produits)
- Synonymes
- anticorps HTT, anticorps hd, anticorps ZHD, anticorps CG9995, anticorps Dmel\\CG9995, anticorps HD, anticorps Hsap\\HD, anticorps Htt, anticorps dHtt, anticorps dhtt, anticorps SLC6A4, anticorps huntington, anticorps it15, anticorps htt, anticorps IT15, anticorps AI256365, anticorps C430023I11Rik, anticorps Hd, anticorps Hdh, anticorps huntingtin, anticorps HTT, anticorps htt, anticorps LOC373520, anticorps Htt
- Sujet
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Synonyms: Huntington disease protein, HTT, HD, IT15, HD protein, huntingtin, huntingtin (Huntington disease), IT15HD
Background: Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington's disease protein is ~350kD in size and is localized in the brain. Anti-Huntington antibody is ideal for investigators interested in Neuroscience research.
Gene Name: HTT
- Pathways
- Signalisation PI3K-Akt, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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