CBS anticorps (AA 1-100)

N° du produit ABIN7489109

Détail du produit anti-CBS anticorps

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), RNA Interference (RNAi)

Fonction: Mouse monoclonal antibody raised against a partial recombinant CBS.

Séquence: MPSETPQAEV GPTGCPHRSG PHSAKGSLEK GSPEDKEAKE PLWIRPDAPS RCTWQLGRPA SESPHHHTAP AKSPKILPDI LKKIGDTPMV RINKIGKKFG

Réactivité croisée: Humain, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: CBS (NP_000062, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3E1

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CBS (ABIN7489109)

Shang, Siow, Isaak, O: "Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury." dans: Oxidative medicine and cellular longevity, Vol. 2016, pp. 9707292, (2016) (PubMed).

Ohmura, Hishiki, Yamamoto, Nakanishi, Kubo, Tsuchihashi, Tamada, Toue, Kabe, Saya, Suematsu: "Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry." dans: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 46, pp. 102-13, (2015) (PubMed).

Yuan, Tang, Lu, Zhou, Zhu, Zhou, Zhang, Hu, Xu: "TLR4 upregulates CBS expression through NF-κB activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity." dans: World journal of gastroenterology, Vol. 21, Issue 28, pp. 8615-28, (2015) (PubMed).

Yang, Wu, Wood, Whiteman, Bian: "Hydrogen sulfide attenuates opioid dependence by suppression of adenylate cyclase/cAMP pathway." dans: Antioxidants & redox signaling, Vol. 20, Issue 1, pp. 31-41, (2014) (PubMed).

Takano, Peng, Kumar, Luo, Hu, Shimoda, Suematsu, Prabhakar, Semenza: "Hypoxia-inducible factors regulate human and rat cystathionine ?-synthase gene expression." dans: The Biochemical journal, Vol. 458, Issue 2, pp. 203-11, (2014) (PubMed).

Takano, Sarfraz, Gilkes, Chaturvedi, Xiang, Suematsu, Zagzag, Semenza: "Decreased expression of cystathionine ?-synthase promotes glioma tumorigenesis." dans: Molecular cancer research : MCR, Vol. 12, Issue 10, pp. 1398-406, (2014) (PubMed).

Miyamoto, Otsuguro, Yamaguchi, Ito: "Contribution of cysteine aminotransferase and mercaptopyruvate sulfurtransferase to hydrogen sulfide production in peripheral neurons." dans: Journal of neurochemistry, Vol. 130, Issue 1, pp. 29-40, (2014) (PubMed).

Ida, Sawa, Ihara, Tsuchiya, Watanabe, Kumagai, Suematsu, Motohashi, Fujii, Matsunaga, Yamamoto, Ono, Devarie-Baez, Xian, Fukuto, Akaike: "Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7606-11, (2014) (PubMed).

Du, Jin, Hong, Li, Wang, Xu, Wang, Zhang, Jia, Liu, Hu: "Downregulation of cystathionine ?-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type." dans: Biochemical and biophysical research communications, Vol. 451, Issue 2, pp. 239-45, (2014) (PubMed).

Yamamoto, Takano, Ishiwata, Ohmura, Nagahata, Matsuura, Kamata, Sakamoto, Nakanishi, Kubo, Hishiki, Suematsu: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." dans: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).

Rashid, Heer, Garle, Alexander, Roberts: "Hydrogen sulphide-induced relaxation of porcine peripheral bronchioles." dans: British journal of pharmacology, Vol. 168, Issue 8, pp. 1902-10, (2013) (PubMed).

Hwang, Sarna, Siow, O: "High-fat diet stimulates hepatic cystathionine β-synthase and cystathionine γ-lyase expression." dans: Canadian journal of physiology and pharmacology, Vol. 91, Issue 11, pp. 913-9, (2013) (PubMed).

Yang, Zhao, Ju, Mani, Cao, Puukila, Khaper, Wu, Wang: "Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2." dans: Antioxidants & redox signaling, Vol. 18, Issue 15, pp. 1906-19, (2013) (PubMed).

Shi, Zhang, Xiao, Hu, Xu: "Electroacupuncture suppresses mechanical allodynia and nuclear factor ? B signaling in streptozotocin-induced diabetic rats." dans: CNS neuroscience & therapeutics, Vol. 19, Issue 2, pp. 83-90, (2013) (PubMed).

Liu, Luo, Liang, Xia, Xu, Chen, Chen: "Actions of hydrogen sulfide and ATP-sensitive potassium channels on colonic hypermotility in a rat model of chronic stress." dans: PLoS ONE, Vol. 8, Issue 2, pp. e55853, (2013) (PubMed).

Zhang, Hu, Zhou, Hu, Wang, Chen, Xiao, Huang, Jiang, Xu: "Promoted interaction of nuclear factor-?B with demethylated cystathionine-?-synthetase gene contributes to gastric hypersensitivity in diabetic rats." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 21, pp. 9028-38, (2013) (PubMed).

Hu, Xu, Miao, Gao, Zhu, Zhou, Xiao, Xu: "Sensitization of sodium channels by cystathionine ?-synthetase activation in colon sensory neurons in adult rats with neonatal maternal deprivation." dans: Experimental neurology, Vol. 248, pp. 275-85, (2013) (PubMed).

Kasparek, Linden, Farrugia, Sarr: "Hydrogen sulfide modulates contractile function in rat jejunum." dans: The Journal of surgical research, Vol. 175, Issue 2, pp. 234-42, (2012) (PubMed).

Guo, Gai, Wang, Jin, Du, Jin: "Characterization of hydrogen sulfide and its synthases, cystathionine ?-synthase and cystathionine ?-lyase, in human prostatic tissue and cells." dans: Urology, Vol. 79, Issue 2, pp. 483.e1-5, (2012) (PubMed).

Dufton, Natividad, Verdu, Wallace: "Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe." dans: Scientific reports, Vol. 2, pp. 499, (2012) (PubMed).

Détails sur CBS

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Autre désignation: CBS (CBS Produits)

Synonymes: anticorps hip4, anticorps GB12529, anticorps CBS, anticorps DDBDRAFT_0189727, anticorps DDBDRAFT_0191292, anticorps DDB_0189727, anticorps DDB_0191292, anticorps cbs, anticorps AI047524, anticorps AI303044, anticorps HIP4, anticorps cb442, anticorps wu:fb37g05, anticorps wu:fm61c07, anticorps wu:fq06c06, anticorps zgc:113704, anticorps cystathionine-beta-synthase L homeolog, anticorps cystathionine-beta-synthase, anticorps cystathionine beta-synthase, anticorps cystathionine beta-synthase CBS, anticorps cystathionine beta synthase, anticorps cystathionine-beta-synthase S homeolog, anticorps cystathionine-beta-synthase b, anticorps cbs.L, anticorps cbs, anticorps Cbs, anticorps CBS, anticorps CNA06170, anticorps Tb11.02.5400, anticorps cysB, anticorps LOC100635325, anticorps cbs.S, anticorps cbsb

Sujet: Full Gene Name: cystathionine-beta-synthase
Synonyms: HIP4

ID gène: 875

NCBI Accession: NM_000071