IL2 Receptor beta anticorps (AA 27-240)
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- Antigène Voir toutes IL2 Receptor beta (IL2RB) Anticorps
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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Épitope
- AA 27-240
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IL2 Receptor beta est non-conjugé
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Application
- Flow Cytometry (FACS), ELISA
- Fonction
- CD122 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CD122 (AA: 27-240) expressed in E. Coli.
- Clone
- 1G11C6
- Isotype
- IgG2b
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Autre désignation
- CD122 (IL2RB Produits)
- Synonymes
- anticorps IL2RB, anticorps il-2rb, anticorps CD122, anticorps IL15RB, anticorps P70-75, anticorps IL2RBC, anticorps IL-15Rbeta, anticorps IL15Rbeta, anticorps Il-2/15Rbeta, anticorps Il-2Rbeta, anticorps p70, anticorps interleukin 2 receptor subunit beta, anticorps interleukin-2 receptor subunit beta, anticorps interleukin 2 receptor, beta, anticorps interleukin 2 receptor, beta chain, anticorps IL2RB, anticorps LOC510185, anticorps il2rb, anticorps Il2rb
- Sujet
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Description: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.
Aliases: IL2RB, IL15RB, P70-75
- Poids moléculaire
- 61kDa
- ID gène
- 3560
- HGNC
- 3560
- UniProt
- P14784
- Pathways
- Signalistation JAK/STAT, Growth Factor Binding
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