IL9 Receptor anticorps (AA 41-270)

N° du produit ABIN5611174

Détail du produit anti-IL9 Receptor anticorps

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Épitope: AA 41-270

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL9 Receptor est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Fonction: CD129 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD129 (AA: 41-270) expressed in E. Coli.

Clone: 4A11H2

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur IL9 Receptor

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Autre désignation: CD129 (IL9R Produits)

Synonymes: anticorps CD129, anticorps IL-9R, anticorps interleukin 9 receptor, anticorps IL9R, anticorps Il9r

Sujet:

Description: The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.

Aliases: IL9R, IL-9R

Poids moléculaire: 57.1kDa

ID gène: 3581

HGNC: 3581

UniProt: Q01113

Pathways: Signalistation JAK/STAT, Growth Factor Binding