Metabotropic Glutamate Receptor 3 anticorps (AA 433-576)
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- Antigène Voir toutes Metabotropic Glutamate Receptor 3 (GRM3) Anticorps
- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
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Épitope
- AA 433-576
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Metabotropic Glutamate Receptor 3 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Fonction
- GRM3 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human GRM3 (AA: 433-576) expressed in E. Coli.
- Clone
- 7A5A6
- Isotype
- IgG2a
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
- Autre désignation
- GRM3 (GRM3 Produits)
- Synonymes
- anticorps GLUR3, anticorps GPRC1C, anticorps MGLUR3, anticorps mGlu3, anticorps 0710001G23Rik, anticorps Gprc1c, anticorps mGluR3, anticorps glutamate metabotropic receptor 3, anticorps glutamate receptor, metabotropic 3, anticorps GRM3, anticorps Grm3
- Sujet
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Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Aliases: GLUR3, mGlu3, GPRC1C, MGLUR3
- Poids moléculaire
- 99kDa
- ID gène
- 2913
- HGNC
- 2913
- UniProt
- Q14832
- Pathways
- cAMP Metabolic Process, Synaptic Membrane
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