Metabotropic Glutamate Receptor 3 anticorps (AA 433-576)

N° du produit ABIN5611177

Détail du produit anti-Metabotropic Glutamate Receptor 3 anticorps

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Épitope: AA 433-576

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human GRM3 (AA: extra 433-576) expressed in E. coli.

Clone: 7A5A6

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur Metabotropic Glutamate Receptor 3

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Autre désignation: GRM3 (GRM3 Produits)

Synonymes: anticorps GLUR3, anticorps GPRC1C, anticorps MGLUR3, anticorps mGlu3, anticorps 0710001G23Rik, anticorps Gprc1c, anticorps mGluR3, anticorps glutamate metabotropic receptor 3, anticorps glutamate receptor, metabotropic 3, anticorps GRM3, anticorps Grm3

Sujet:

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Aliases: GLUR3, mGlu3, GPRC1C, MGLUR3

Poids moléculaire: 99 kDa

ID gène: 2913

HGNC: 2913

Pathways: cAMP Metabolic Process, Synaptic Membrane