Metabotropic Glutamate Receptor 5 anticorps (AA 458-580)
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- Antigène Voir toutes Metabotropic Glutamate Receptor 5 (GRM5) Anticorps
- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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Épitope
- AA 458-580
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Metabotropic Glutamate Receptor 5 est non-conjugé
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Application
- Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- Fonction
- GRM5 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human GRM5 (AA: 458-580) expressed in E. Coli.
- Clone
- 1A11D10
- Isotype
- IgG1
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- Indications d'application
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
- Autre désignation
- GRM5 (GRM5 Produits)
- Synonymes
- anticorps GPRC1E, anticorps MGLUR5, anticorps mGlu5, anticorps mGluR5, anticorps mGlur5, anticorps 6430542K11Rik, anticorps AI850523, anticorps Glu5R, anticorps Gprc1e, anticorps mGluR5b, anticorps glutamate receptor, metabotropic 5, anticorps glutamate metabotropic receptor 5, anticorps GRM5, anticorps Grm5
- Sujet
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Description: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
Aliases: mGlu5, GPRC1E, MGLUR5, PPP1R86
- Poids moléculaire
- 132.5kDa
- ID gène
- 2915
- HGNC
- 2915
- UniProt
- P41594
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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