Metabotropic Glutamate Receptor 6 anticorps (AA 480-585)
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- Antigène Voir toutes Metabotropic Glutamate Receptor 6 (GRM6) Anticorps
- Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
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Épitope
- AA 480-585
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Metabotropic Glutamate Receptor 6 est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS)
- Fonction
- GRM6 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human GRM6 (AA: 480-585) expressed in E. Coli.
- Clone
- 7D9C9
- Isotype
- IgG1
- Top Product
- Discover our top product GRM6 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
- Autre désignation
- GRM6 (GRM6 Produits)
- Sujet
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Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Aliases: mGlu6, CSNB1B, GPRC1F, MGLUR6
- Poids moléculaire
- 95.5kDa
- ID gène
- 2916
- HGNC
- 2916
- UniProt
- O15303
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