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Metabotropic Glutamate Receptor 6 anticorps (AA 480-585)

GRM6 Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 7D9C9 unconjugated
N° du produit ABIN5611180
  • Antigène Voir toutes Metabotropic Glutamate Receptor 6 (GRM6) Anticorps
    Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
    Épitope
    • 12
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 480-585
    Reactivité
    • 35
    • 12
    • 11
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 35
    • 2
    Souris
    Clonalité
    • 36
    • 1
    Monoclonal
    Conjugué
    • 28
    • 3
    • 2
    • 2
    • 1
    • 1
    Cet anticorp Metabotropic Glutamate Receptor 6 est non-conjugé
    Application
    • 31
    • 17
    • 11
    • 5
    • 5
    • 3
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Fonction
    GRM6 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human GRM6 (AA: 480-585) expressed in E. Coli.
    Clone
    7D9C9
    Isotype
    IgG1
    Top Product
    Discover our top product GRM6 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
    Autre désignation
    GRM6 (GRM6 Produits)
    Sujet

    Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

    Aliases: mGlu6, CSNB1B, GPRC1F, MGLUR6

    Poids moléculaire
    95.5kDa
    ID gène
    2916
    HGNC
    2916
    UniProt
    O15303
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