Axin anticorps (AA 546-752)

N° du produit ABIN5611198

Détail du produit anti-Axin anticorps

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Épitope: AA 546-752

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Axin est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: AXIN1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human AXIN1 (AA: 546-752) expressed in E. Coli.

Clone: 4E9F1

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/50 - 1/250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Axin

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Autre désignation: AXIN1 (AXIN1 Produits)

Synonymes: anticorps AXIN1, anticorps axin, anticorps fused, anticorps xAxin, anticorps LOC100226467, anticorps AXIN, anticorps PPP1R49, anticorps AI316800, anticorps Axin, anticorps Fu, anticorps Kb, anticorps Ki, anticorps kinky, anticorps knobbly, anticorps AXIN1-RGS, anticorps wu:fi22e03, anticorps wu:fj14c08, anticorps wu:fk11b03, anticorps zgc:109872, anticorps axin 1, anticorps axin 1 S homeolog, anticorps axin 1 L homeolog, anticorps AXIN1, anticorps axin1.S, anticorps axin1.L, anticorps Axin1, anticorps axin1

Sujet:

Description: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.

Aliases: AXIN, PPP1R49

Poids moléculaire: 95.6kDa

ID gène: 8312

HGNC: 8312

UniProt: O15169

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling