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CCR5 anticorps

CCR5 Reactivité: Humain WB, ELISA, FACS, IHC Hôte: Souris Monoclonal 6G11D1 unconjugated
N° du produit ABIN5611203
  • Antigène Voir toutes CCR5 Anticorps
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Reactivité
    • 163
    • 50
    • 36
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 106
    • 43
    • 20
    • 6
    • 4
    Souris
    Clonalité
    • 109
    • 64
    • 3
    Monoclonal
    Conjugué
    • 85
    • 15
    • 13
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCR5 est non-conjugé
    Application
    • 93
    • 74
    • 69
    • 21
    • 21
    • 18
    • 16
    • 14
    • 14
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
    Fonction
    CD195 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human CD195 (AA: mix) expressed in E. Coli.
    Clone
    6G11D1
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Autre désignation
    CD195 (CCR5 Produits)
    Synonymes
    anticorps CC-CKR-5, anticorps CCCKR5, anticorps CCR-5, anticorps CD195, anticorps CKR-5, anticorps CKR5, anticorps CMKBR5, anticorps IDDM22, anticorps Ckr5, anticorps Cmkbr5, anticorps CCR1-L, anticorps GPCR, anticorps CCR5, anticorps AM4-7, anticorps C-C motif chemokine receptor 5 (gene/pseudogene), anticorps chemokine (C-C motif) receptor 5, anticorps C-C motif chemokine receptor 5, anticorps CCR5, anticorps Ccr5
    Sujet

    Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles, the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.

    Aliases: CCR5, CKR5, CCR-5, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5

    Poids moléculaire
    40.5kDa
    ID gène
    1234
    HGNC
    1234
    UniProt
    P51681
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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