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BAX anticorps (AA 13-160)

Name: BAX anticorps (AA 13-160)
Brand: antibodies-online
SKU: ABIN5611252
Price: 614.71 EUR
Availability: InStock

BAX Reactivité: Humain WB, ELISA, IHC, FACS, ICC, Neut Hôte: Souris Monoclonal 4H9B11 unconjugated

Western blot analysis using BAX mAb against human BAX (AA: 13-160) recombinant protein. (BAX anticorps (AA 13-160))

Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using BAX mouse mAb with DAB staining. (BAX anticorps (AA 13-160))

IHC

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng) (BAX anticorps (AA 13-160))

ELISA

Western blot analysis using BAX mAb against HEK293 (1) and BAX (AA: 13-160)-hIgGFc transfected HEK293 (2) cell lysate. (BAX anticorps (AA 13-160))

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using BAX mouse mAb with DAB staining. (BAX anticorps (AA 13-160))

IHC

5 images

N° du produit ABIN5611252

Fiche de données

Antigène Voir toutes BAX Anticorps

BAX (BCL2-Associated X Protein (BAX))
Épitope
38

32

18

17

15

12

11

10

9

8

8

7

6

5

4

4

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 13-160
Reactivité
260

159

143

47

32

27

25

18

16

13

9

5

3

3

3

2

1

1

1

1

1
Humain
Hôte
171

97

3

1
Souris
Anticorps secondaires appropriés
Clonalité
185

87
Monoclonal
Conjugué
137

16

13

12

10

7

5

5

5

5

5

5

5

5

5

5

5

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Cet anticorp BAX est non-conjugé
Application
236

113

74

62

52

52

51

40

38

12

12

8

5

3

1

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification

purified

Immunogène

Purified recombinant fragment of human BAX (AA: 13-160) expressed in E. coli.

Clone

4H9B11

Isotype

IgG2a

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Indications d'application

ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: 1:200 - 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C/-20 °C

Stockage commentaire

4°C, -20°C for long term storage
Antigène

BAX (BCL2-Associated X Protein (BAX))

Autre désignation

BAX (BAX Produits)

Synonymes

anticorps BAX-ALPHA, anticorps bax-A, anticorps xBax, anticorps xlbax, anticorps BAX, anticorps bax, anticorps fj16e01, anticorps wu:fc50b10, anticorps wu:fj16e01, anticorps BCL2L4, anticorps zgc:112983, anticorps BCL2 associated X, apoptosis regulator, anticorps BCL2-associated X protein L homeolog, anticorps BCL2-associated X protein, anticorps bcl2-associated X protein, a, anticorps bcl2-associated X protein, b, anticorps BAX, anticorps bax.L, anticorps bax, anticorps baxa, anticorps Bax, anticorps baxb

Sujet

Description: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Aliases: BCL2L4

Poids moléculaire

21.2 kDa

ID gène

581

HGNC

581

Pathways

Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response