BCL6 anticorps (AA 147-276)
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- Antigène Voir toutes BCL6 Anticorps
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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Épitope
- AA 147-276
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BCL6 est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Fonction
- BCL6 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human BCL6 (AA: 147-276) expressed in E. Coli.
- Clone
- 2G1B6
- Isotype
- IgG1
- Top Product
- Discover our top product BCL6 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
- Autre désignation
- BCL6 (BCL6 Produits)
- Synonymes
- anticorps bcl5, anticorps laz3, anticorps bcl6a, anticorps znf51, anticorps zbtb27, anticorps MGC132260, anticorps Bcl5, anticorps BCL5, anticorps BCL6A, anticorps LAZ3, anticorps ZBTB27, anticorps ZNF51, anticorps B-cell CLL/lymphoma 6 L homeolog, anticorps B-cell CLL/lymphoma 6, anticorps B cell leukemia/lymphoma 6, anticorps bcl6.L, anticorps bcl6, anticorps BCL6, anticorps Bcl6
- Sujet
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Description: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Aliases: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27
- Poids moléculaire
- 78.8kDa
- ID gène
- 604
- HGNC
- 604
- UniProt
- P41182
- Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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