CCR1 anticorps
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- Antigène Voir toutes CCR1 Anticorps
- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CCR1 est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human CD191 (AA: extra mix) expressed in E. coli.
- Clone
- 8E10G6
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
- Autre désignation
- CD191 (CCR1 Produits)
- Synonymes
- anticorps CD191, anticorps CKR-1, anticorps CKR1, anticorps CMKBR1, anticorps HM145, anticorps MIP1aR, anticorps SCYAR1, anticorps Cmkbr1, anticorps Mip-1a-R, anticorps C-C motif chemokine receptor 1, anticorps chemokine (C-C motif) receptor 1, anticorps CCR1, anticorps Ccr1
- Sujet
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Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Aliases: CCR1, CKR1, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1
- Poids moléculaire
- 41.2 kDa
- ID gène
- 1230
- HGNC
- 1230
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