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CD276 anticorps (AA 29-466)

CD276 Reactivité: Humain ELISA, FACS, IHC, ICC Hôte: Souris Monoclonal 8C1C2 unconjugated
N° du produit ABIN5611271
  • Antigène Voir toutes CD276 Anticorps
    CD276
    Épitope
    • 15
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-466
    Reactivité
    • 65
    • 36
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 47
    • 17
    • 9
    • 1
    Souris
    Clonalité
    • 43
    • 30
    • 1
    Monoclonal
    Conjugué
    • 38
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD276 est non-conjugé
    Application
    • 45
    • 22
    • 22
    • 14
    • 13
    • 9
    • 8
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Fonction
    B7H3 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human B7H3 (AA: 29-466) expressed in HEK293 cells.
    Clone
    8C1C2
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    CD276
    Autre désignation
    B7H3 (CD276 Produits)
    Synonymes
    anticorps sc:d0645, anticorps zgc:158279, anticorps 6030411F23Rik, anticorps AU016588, anticorps B7RP-2, anticorps B7h3, anticorps B7H3, anticorps 4Ig-B7-H3, anticorps B7-H3, anticorps CD276 molecule, anticorps CD276 molecule S homeolog, anticorps CD276 antigen, anticorps Cd276 molecule, anticorps CD276, anticorps cd276.S, anticorps cd276, anticorps Cd276
    Sujet

    Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Aliases: CD276, B7-H3, B7RP-2, 4Ig-B7-H3

    Poids moléculaire
    57.2kDa
    ID gène
    80381
    HGNC
    80381
    UniProt
    Q5ZPR3
    Pathways
    Cancer Immune Checkpoints
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