DDR1 anticorps (AA 21-176)

N° du produit ABIN5611283

Détail du produit anti-DDR1 anticorps

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Épitope: AA 21-176

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DDR1 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: CD167 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD167 (AA: 21-176) expressed in E. Coli.

Clone: 4F2C12

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DDR1

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Autre désignation: CD167 (DDR1 Produits)

Synonymes: anticorps CG11573, anticorps CG13984, anticorps CG13985, anticorps CG33531, anticorps CG9488, anticorps CG9490, anticorps CT33540, anticorps DDR, anticorps Dmel\\CG33531, anticorps Dmel_CG13984, anticorps 6030432F18, anticorps AI323681, anticorps CD167a, anticorps Cak, anticorps Nep, anticorps PTK3A, anticorps CAK, anticorps CD167, anticorps EDDR1, anticorps HGK2, anticorps MCK10, anticorps NEP, anticorps NTRK4, anticorps PTK3, anticorps RTK6, anticorps TRKE, anticorps Drd1, anticorps PTK3D, anticorps Discoidin domain receptor, anticorps discoidin domain receptor family, member 1, anticorps discoidin domain receptor tyrosine kinase 1, anticorps Ddr, anticorps Ddr1, anticorps DDR1

Sujet:

Description: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Aliases: DDR1,CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, EDDR1, MCK10, NTRK4, PTK3A

Poids moléculaire: 101kDa

ID gène: 780

HGNC: 780

UniProt: Q08345

Pathways: Signalisation RTK, Smooth Muscle Cell Migration