BCL2L10 anticorps (AA 31-186)

N° du produit ABIN5611302

Détail du produit anti-BCL2L10 anticorps

Antigène: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Épitope: AA 31-186

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL2L10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. coli.

Clone: 8A2F9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur BCL2L10

Antigène: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Autre désignation: BCL2L10 (BCL2L10 Produits)

Synonymes: anticorps BCL-B, anticorps Boo, anticorps Diva, anticorps AA420380, anticorps AU023065, anticorps C85687, anticorps NR-13, anticorps mcl1l, anticorps nr13, anticorps sb:cb78, anticorps BCL2 like 10, anticorps Bcl2-like 10, anticorps BCL2-like 10 (apoptosis facilitator), anticorps BCL2L10, anticorps Bcl2l10, anticorps bcl2l10

Sujet:

Description: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Aliases: Boo, Diva, BCL-B, bcl2-L-10

Poids moléculaire: 22 kDa

ID gène: 10017

HGNC: 10017

Pathways: Positive Regulation of Endopeptidase Activity