BCL2L10 anticorps (AA 31-186)

N° du produit ABIN5611303

Détail du produit anti-BCL2L10 anticorps

Antigène: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Épitope: AA 31-186

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL2L10 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: BCL2L10 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. Coli.

Clone: 8A11G12

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur BCL2L10

Antigène: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Autre désignation: BCL2L10 (BCL2L10 Produits)

Synonymes: anticorps BCL-B, anticorps Boo, anticorps Diva, anticorps AA420380, anticorps AU023065, anticorps C85687, anticorps NR-13, anticorps mcl1l, anticorps nr13, anticorps sb:cb78, anticorps BCL2 like 10, anticorps Bcl2-like 10, anticorps BCL2-like 10 (apoptosis facilitator), anticorps BCL2L10, anticorps Bcl2l10, anticorps bcl2l10

Sujet:

Description: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Aliases: Boo, Diva, BCL-B, bcl2-L-10

Poids moléculaire: 22kDa

ID gène: 10017

HGNC: 10017

UniProt: Q9HD36

Pathways: Positive Regulation of Endopeptidase Activity