CD207 anticorps (AA 155-328)

N° du produit ABIN5611331

Détail du produit anti-CD207 anticorps

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Épitope: AA 155-328

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD207 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: CD207 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD207 (AA: 155-328) expressed in E. Coli.

Clone: 1C5A1

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: CD207 (CD207 Produits)

Synonymes: anticorps CD207, anticorps CLEC4K, anticorps RGD1565913, anticorps CD207 molecule, anticorps CD207 antigen, anticorps CD207, anticorps Cd207

Sujet:

Description: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

Aliases: CLEC4K

Poids moléculaire: 36.7kDa

ID gène: 50489

HGNC: 50489

UniProt: Q9UJ71