GLRB anticorps (AA 23-160)
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- Antigène Voir toutes GLRB Anticorps
- GLRB (Glycine Receptor, beta (GLRB))
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Épitope
- AA 23-160
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GLRB est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FACS), Neutralization (Neut)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human GLRB (AA: extra 23-160) expressed in E. coli.
- Clone
- 3B8A8
- Isotype
- IgG2b
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: N/A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- GLRB (Glycine Receptor, beta (GLRB))
- Autre désignation
- GLRB (GLRB Produits)
- Synonymes
- anticorps HKPX2, anticorps glrb, anticorps MGC145156, anticorps AI853901, anticorps Glyrb, anticorps spa, anticorps spastic, anticorps glrb2, anticorps zgc:101041, anticorps glycine receptor beta, anticorps glycine receptor, beta, anticorps glycine receptor, beta subunit, anticorps glycine receptor, beta b, anticorps GLRB, anticorps Glrb, anticorps glrb, anticorps glrbb
- Sujet
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Description: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
Aliases: HKPX2
- Poids moléculaire
- 56.1 kDa
- ID gène
- 2743
- HGNC
- 2743
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