GLRB anticorps (AA 23-160)

N° du produit ABIN5611340

Détail du produit anti-GLRB anticorps

Antigène: GLRB (Glycine Receptor, beta (GLRB))

Épitope: AA 23-160

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLRB est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: GLRB Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human GLRB (AA: 23-160) expressed in E. Coli.

Clone: 3B8A8

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur GLRB

Antigène: GLRB (Glycine Receptor, beta (GLRB))

Autre désignation: GLRB (GLRB Produits)

Synonymes: anticorps HKPX2, anticorps glrb, anticorps MGC145156, anticorps AI853901, anticorps Glyrb, anticorps spa, anticorps spastic, anticorps glrb2, anticorps zgc:101041, anticorps glycine receptor beta, anticorps glycine receptor, beta, anticorps glycine receptor, beta subunit, anticorps glycine receptor, beta b, anticorps GLRB, anticorps Glrb, anticorps glrb, anticorps glrbb

Sujet:

Description: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Aliases: HKPX2

Poids moléculaire: 56.1kDa

ID gène: 2743

HGNC: 2743

UniProt: P48167