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PSMA anticorps (AA 44-177)

FOLH1 Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 2D10E10 unconjugated
N° du produit ABIN5611345
  • Antigène Voir toutes PSMA (FOLH1) Anticorps
    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
    Épitope
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-177
    Reactivité
    • 69
    • 11
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 35
    • 35
    • 1
    Souris
    Clonalité
    • 39
    • 32
    Monoclonal
    Conjugué
    • 49
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PSMA est non-conjugé
    Application
    • 37
    • 25
    • 25
    • 13
    • 11
    • 10
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Fonction
    PSMA Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human PSMA (AA: 44-177) expressed in E. Coli.
    Clone
    2D10E10
    Isotype
    IgG1
    Top Product
    Discover our top product FOLH1 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
    Autre désignation
    PSMA (FOLH1 Produits)
    Sujet

    Description: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.

    Aliases: FOLH1, PSM, FGCP, FOLH, GCP2, mGCP, GCPII, NAALAD1, NAALAdase

    Poids moléculaire
    84.3kDa
    ID gène
    2346
    HGNC
    2346
    UniProt
    Q04609
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