ATRX anticorps (AA 2311-2492)
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- Antigène Voir toutes ATRX Anticorps
- ATRX (helicase 2, X-linked (ATRX))
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Épitope
- AA 2311-2492
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ATRX est non-conjugé
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Application
- ELISA
- Fonction
- ATRX Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human ATRX (AA: 2311-2492) expressed in E. Coli.
- Clone
- 8B2H9
- Isotype
- IgG1
- Top Product
- Discover our top product ATRX Anticorps primaire
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- ATRX (helicase 2, X-linked (ATRX))
- Autre désignation
- ATRX (ATRX Produits)
- Synonymes
- anticorps ATR2, anticorps JMS, anticorps MRXHF1, anticorps RAD54, anticorps RAD54L, anticorps SFM1, anticorps SHS, anticorps XH2, anticorps XNP, anticorps ZNF-HX, anticorps 4833408C14Rik, anticorps AI447451, anticorps DXHXS6677E, anticorps HP1-BP38, anticorps Hp1bp2, anticorps Hp1bp38, anticorps MRXS3, anticorps Rad54, anticorps Xnp, anticorps atrx, anticorps rad54, anticorps atrxl, anticorps wu:fb26e12, anticorps wu:fb52h08, anticorps wu:fb72g09, anticorps wu:fb94e07, anticorps zgc:66223, anticorps ATRX, chromatin remodeler, anticorps alpha thalassemia/mental retardation syndrome X-linked L homeolog, anticorps alpha thalassemia/mental retardation syndrome X-linked homolog (human), anticorps ATRX, anticorps Atrx, anticorps atrx.L, anticorps atrx
- Sujet
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Description: The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Aliases: JMS, SHS, XH2, XNP, ATR2, SFM1, MRX52, RAD54, MRXHF1, RAD54L, ZNF-HX
- Poids moléculaire
- 282.5kDa
- ID gène
- 546
- HGNC
- 546
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