KPNA1 anticorps (AA 1-538)

N° du produit ABIN561614

Détail du produit anti-KPNA1 anticorps

Antigène: KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

Épitope: AA 1-538

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KPNA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse monoclonal antibody raised against a full length recombinant KPNA1.

Séquence: MTTPGKENFR LKSYKNKSLN PDEMRRRREE EGLQLRKQKR EEQLFKRRNV ATAEEETEEE VMSDGGFHEA QINNMEMAPG GVITSDMIEM IFSKSPEQQL SATQKFRKLL SKEPNPPIDE VISTPGVVAR FVEFLKRKEN CTLQFESAWV LTNIASGNSL QTRIVIQAGA VPIFIELLSS EFEDVQEQAV WALGNIAGDS TMCRDYVLDC NILPPLLQLF SKQNRLTMTR NAVWALSNLC RGKSPPPEFA KVSPCLNVLS WLLFVSDTDV LADACWALSY LSDGPNDKIQ AVIDAGVCRR LVELLMHNDY KVVSPALRAV GNIVTGDDIQ TQVILNCSAL QSLLHLLSSP KESIKKEACW TISNITAGNR AQIQTVIDAN IFPALISILQ TAEFRTRKEA AWAITNATSG GSAEQIKYLV ELGCIKPLCD LLTVMDSKIV QVALNGLENI LRLGEQEAKR NGTGINPYCA LIEEAYGLDK IEFLQSHENQ EIYQKAFDLI EHYFGTEDED SSIAPQVDLN QQQYIFQQCE APMEGFQL

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: KPNA1 (AAH02374.1, 1 a.a. ~ 538 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2A4-1B5

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-KPNA1 (ABIN561614)

Moriyama, Sangel, Yamaguchi, Obuse, Miyamoto, Oka, Yoneda: "Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box." dans: Biochemical and biophysical research communications, Vol. 462, Issue 3, pp. 201-7, (2015) (PubMed).

Moriyama, Nagai, Oka, Ikawa, Okabe, Yoneda: "Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery." dans: The FEBS journal, Vol. 278, Issue 9, pp. 1561-72, (2011) (PubMed).

Nishimura, Zupunski, Troakes, Kathe, Fratta, Howell, Gallo, Hortobágyi, Shaw, Rogelj: "Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration." dans: Brain : a journal of neurology, Vol. 133, Issue Pt 6, pp. 1763-71, (2010) (PubMed).

Détails sur KPNA1

Antigène: KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

Autre désignation: KPNA1 (KPNA1 Produits)

Sujet: Full Gene Name: karyopherin alpha 1 (importin alpha 5)
Synonyms: IPOA5,NPI-1,RCH2,SRP1

ID gène: 3836

Pathways: M Phase, Protein targeting to Nucleus