K-RAS anticorps (AA 1-188)

N° du produit ABIN561621

Détail du produit anti-K-RAS anticorps

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Épitope: AA 1-188

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp K-RAS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Fonction: Mouse monoclonal antibody raised against a full length recombinant KRAS.

Séquence: MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKCVIM

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: KRAS (AAH13572, 1 a.a. ~ 188 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3B10-2F2

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-K-RAS (ABIN561621)

Madureira, Bharadwaj, Bydoun, Garant, OConnell, Lee, Waisman: "Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." dans: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).

King, Bray, Galbraith, Christie, Fleming: "Evidence for aldosterone-dependent growth of renal cell carcinoma." dans: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).

Ambrosini, Khanin, Carvajal, Schwartz: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." dans: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).

Valtorta, Misale, Sartore-Bianchi, Nagtegaal, Paraf, Lauricella, Dimartino, Hobor, Jacobs, Ercolani, Lamba, Scala, Veronese, Laurent-Puig, Siena, Tejpar, Mottolese, Punt, Gambacorta, Bardelli et al.: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." dans: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).

Fuentes-Calvo, Blázquez-Medela, Santos, López-Novoa, Martínez-Salgado: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." dans: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).

Détails sur K-RAS

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Autre désignation: KRAS (KRAS Produits)

Synonymes: anticorps wu:fa04e08, anticorps wu:fc14b12, anticorps wu:fc23g10, anticorps wu:fj89d12, anticorps zgc:85725, anticorps Kras2, anticorps c-Ki-ras, anticorps p21, anticorps C-K-RAS, anticorps CFC2, anticorps K-RAS2A, anticorps K-RAS2B, anticorps K-RAS4A, anticorps K-RAS4B, anticorps KI-RAS, anticorps KRAS1, anticorps KRAS2, anticorps NS, anticorps NS3, anticorps RASK2, anticorps AI929937, anticorps K-ras, anticorps Ki-ras, anticorps Kras-2, anticorps p21B, anticorps ras, anticorps k-ras, anticorps kras, anticorps kras-a, anticorps kras-b, anticorps rask2, anticorps K-RAS, anticorps p21ras, anticorps KRAS proto-oncogene, GTPase, anticorps v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, anticorps Kirsten rat sarcoma viral oncogene homolog, anticorps semicolonial-7, anticorps Ras family protein, anticorps GTPase KRas, anticorps Kirsten rat sarcoma viral oncogene homolog S homeolog, anticorps KRAS, anticorps kras, anticorps Kras, anticorps smco-7, anticorps PGTG_03066, anticorps Tsp_02666, anticorps Tsp_01642, anticorps rask, anticorps kras.S

Classe de substances: Viral Protein

Sujet: Full Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Synonyms: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2

ID gène: 3845