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LETM1 anticorps (AA 601-708)

LETM1 Reactivité: Humain WB, ELISA, IF, IP, IHC (p) Hôte: Souris Monoclonal 6F7 unconjugated
N° du produit ABIN561659
  • Antigène Voir toutes LETM1 Anticorps
    LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))
    Épitope
    • 15
    • 10
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-708
    Reactivité
    • 56
    • 15
    • 11
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 2
    Souris
    Clonalité
    • 56
    Monoclonal
    Conjugué
    • 28
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LETM1 est non-conjugé
    Application
    • 52
    • 24
    • 13
    • 13
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Mouse monoclonal antibody raised against a partial recombinant LETM1.
    Séquence
    ESKASKRLTK RVQQMIGQID GLISQLEMDQ QAGKLAPANG MPTGENVISV AELINAMKQV KHIPESKLTS LAAALDENKD GKVNIDDLVK VIELVDKEDV HISTSQVA
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    LETM1 (NP_036450, 601 a.a. ~ 708 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    6F7
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Chen, Yang, Liu, Piao, Zhang, Lin, Li: "High expression of leucine zipper-EF-hand containing transmembrane protein 1 predicts poor prognosis in head and neck squamous cell carcinoma." dans: BioMed research international, Vol. 2014, pp. 850316, (2014) (PubMed).

    Doonan, Chandramoorthy, Hoffman, Zhang, Cárdenas, Shanmughapriya, Rajan, Vallem, Chen, Foskett, Cheung, Houser, Madesh: "LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 11, pp. 4936-49, (2014) (PubMed).

    Shin, Chung, Kang, Jiang, Yu, Han, Chae, Moon, Jang, Cho: "Co-delivery of LETM1 and CTMP synergistically inhibits tumor growth in H-ras12V liver cancer model mice." dans: Cancer gene therapy, Vol. 20, Issue 3, pp. 186-94, (2013) (PubMed).

    Piao, Li, Kim, Sohn, Yang, Park, Byun, Won, Hong, Hur, Seok, Shong, Sack, Brazil, Hemmings, Park: "Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis." dans: Cellular signalling, Vol. 21, Issue 5, pp. 767-77, (2009) (PubMed).

    Piao, Li, Kim, Byun, Huang, Hwang, Yang, Park, Won, Hong, Hur, Seok, Shong, Cho, Brazil, Hemmings, Park: "Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death." dans: Cancer research, Vol. 69, Issue 8, pp. 3397-404, (2009) (PubMed).

    Dimmer, Navoni, Casarin, Trevisson, Endele, Winterpacht, Salviati, Scorrano: "LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability." dans: Human molecular genetics, Vol. 17, Issue 2, pp. 201-14, (2008) (PubMed).

  • Antigène
    LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))
    Autre désignation
    LETM1 (LETM1 Produits)
    Synonymes
    anticorps LETM1, anticorps wu:fc31h08, anticorps wu:fc58h01, anticorps zgc:109969, anticorps letm1, anticorps MGC145623, anticorps leucine zipper and EF-hand containing transmembrane protein 1, anticorps leucine zipper-EF-hand containing transmembrane protein 1, anticorps LETM1 and EF-hand domain-containing protein 1, mitochondrial, anticorps LETM1, anticorps letm1, anticorps LOC100346816, anticorps Letm1
    Sujet
    Full Gene Name: leucine zipper-EF-hand containing transmembrane protein 1
    Synonyms:
    ID gène
    3954
    NCBI Accession
    NM_012318
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