PDK3
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Conseil sur la manipulation
Aliquot to avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Hwang, Wu, Harris: "Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet." dans: The FEBS journal, Vol. 279, Issue 10, pp. 1883-93, (2012) (PubMed).
Jeoung, Harris: "Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice." dans: American journal of physiology. Endocrinology and metabolism, Vol. 295, Issue 1, pp. E46-54, (2008) (PubMed).
Lu, Lin, Chen, Lai, Tsai: "Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance." dans: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28106-14, (2008) (PubMed).