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Progesterone Receptor anticorps (AA 1-110)

Name: Progesterone Receptor anticorps (AA 1-110)
SKU: ABIN562204
Price: 661.92 EUR
Availability: InStock

PGR Reactivité: Humain WB, ELISA, IHC (p), IF Hôte: Souris Monoclonal 5D10 unconjugated

Western Blot detection against Immunogen (37. (Progesterone Receptor anticorps (AA 1-110))

Immunofluorescence of monoclonal antibody to PGR on MCF-7 cell. (Progesterone Receptor anticorps (AA 1-110))

Detection limit for recombinant GST tagged PGR is approximately 0. (Progesterone Receptor anticorps (AA 1-110))

ELISA

Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human breast cancer. (Progesterone Receptor anticorps (AA 1-110))

IHC (fp)

ISt

5 images

(2 références)

N° du produit ABIN562204

Fiche de données

Antigène Voir toutes Progesterone Receptor (PGR) Anticorps

Progesterone Receptor (PGR)
Épitope
16

15

15

14

14

12

11

10

10

8

8

8

7

7

7

7

6

6

5

5

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-110
Reactivité
245

45

42

16

15

8

6

6

5

3

3

2

1

1

1

1

1
Humain
Hôte
188

60

1

1
Souris
Anticorps secondaires appropriés
Clonalité
185

65
Monoclonal
Conjugué
121

21

11

11

8

7

6

6

6

6

6

6

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
Cet anticorp Progesterone Receptor est non-conjugé
Application
177

89

60

30

27

26

26

22

18

18

17

10

6

3

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Fonction

Mouse monoclonal antibody raised against a partial recombinant PGR. This PGR gene uses two distinct promoters and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B. Our immunogen corresponds to the specific region of isoform B, thus this antibody is a PGR isofrom B specific antibody.

Séquence

MTELKAKGPR APHVAGGPPS PEVGSPLLCR PAAGPFPGSQ TSDTLPEVSA IPISLDGLLF PRPCQGQDPS DEKTQDQQSL SDVEGAYSRA EATRGAGGSS SSPPEKDSGL

Réactivité croisée

Humain, Rat

Attributs du produit

Antibody Reactive Against Recombinant Protein.

Immunogène

PGR (NP_000917, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

5D10

Isotype

IgG1

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Indications d'application

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

In 1x PBS, pH 7.4

Conseil sur la manipulation

Aliquot to avoid repeated freezing and thawing.

Stock

-20 °C

Stockage commentaire

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liu, Chang, Kuo, Hwa, Lin, Huang, Chen, Chang, Hsieh: "Major Functional Transcriptome of an Inferred Center Regulator of an ER(-) Breast Cancer Model System." dans: Cancer informatics, Vol. 11, pp. 87-111, (2012) (PubMed).

Liu, Chang, Kuo, Hwa, Shyu, Chang, Hsieh: "In Silico Prediction for Regulation of Transcription Factors onTheir Shared Target Genes Indicates Relevant Clinical Implications in a Breast Cancer Population." dans: Cancer informatics, Vol. 11, pp. 113-37, (2012) (PubMed).
Antigène

Progesterone Receptor (PGR)

Autre désignation

PGR (PGR Produits)

Synonymes

anticorps NR3C3, anticorps PR, anticorps 9930019P03Rik, anticorps BB114106, anticorps ENSMUSG00000074510, anticorps PR-A, anticorps PR-B, anticorps XPR-1, anticorps pgr, anticorps xpr-2, anticorps LOC443444, anticorps PGR, anticorps pg, anticorps pr, anticorps gb:dq017620, anticorps progesterone receptor, anticorps progesterone receptor L homeolog, anticorps PGR, anticorps Pgr, anticorps pgr.L, anticorps pgr

Sujet

Full Gene Name: progesterone receptor
Synonyms: NR3C3,PR

ID gène

5241

NCBI Accession

NM_000926

Pathways

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration