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CD41, CD61 anticorps

Reactivité: Humain FACS, IP, ICC Hôte: Souris Monoclonal PAC-1 unconjugated
N° du produit ABIN5633262
  • Antigène Voir toutes CD41, CD61 Anticorps
    CD41, CD61 (CD41,CD61)
    Reactivité
    • 17
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 25
    Souris
    Clonalité
    • 25
    Monoclonal
    Conjugué
    • 10
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD41, CD61 est non-conjugé
    Application
    • 21
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificité
    The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Human platelets
    Clone
    PAC-1
    Isotype
    IgM kappa
    Top Product
    Discover our top product CD41, CD61 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 2-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    CD41, CD61 (CD41,CD61)
    Autre désignation
    CD41/CD61 (CD41, CD61 Produits)
    Sujet
    CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.,platelet GPIIb, Integrin alpha-Iib, GPalpha IIb, GPIIb, GT, GP3A, platelet GPIIIa
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