AGR2 anticorps (AA 1-175)

N° du produit ABIN564604

Détail du produit anti-AGR2 anticorps

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Épitope: AA 1-175

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AGR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Mouse monoclonal antibody raised against a full length recombinant AGR2.

Séquence: MEKIPVSAFL LLVALSYTLA RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: AGR2 (AAH15503.1, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1C3

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-AGR2 (ABIN564604)

Dong, Wodziak, Lowe: "Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface." dans: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8016-27, (2015) (PubMed).

Riener, Thiesler, Hellerbrand, Amann, Cathomas, Fritzsche, Dahl, Bahra, Weichert, Terracciano, Kristiansen: "Loss of anterior gradient-2 expression is an independent prognostic factor in colorectal carcinomas." dans: European journal of cancer (Oxford, England : 1990), Vol. 50, Issue 10, pp. 1722-30, (2014) (PubMed).

Gray, Murray, Nowicki, Remnant, Scherl, Muller, Vojtesek, Hupp: "Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein." dans: Protein science : a publication of the Protein Society, Vol. 22, Issue 9, pp. 1266-78, (2013) (PubMed).

Wayner, Quek, Ahmad, Ho, Loprieno, Zhou, Ellis, True, Liu: "Development of an ELISA to detect the secreted prostate cancer biomarker AGR2 in voided urine." dans: The Prostate, Vol. 72, Issue 9, pp. 1023-34, (2012) (PubMed).

Darb-Esfahani, Fritzsche, Kristiansen, Weichert, Sehouli, Braicu, Dietel, Denkert: "Anterior gradient protein 2 (AGR2) is an independent prognostic factor in ovarian high-grade serous carcinoma." dans: Virchows Archiv : an international journal of pathology, Vol. 461, Issue 2, pp. 109-16, (2012) (PubMed).

Lepreux, Bioulac-Sage, Chevet: "Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree." dans: Liver international : official journal of the International Association for the Study of the Liver, Vol. 31, Issue 3, pp. 322-8, (2011) (PubMed).

Ambolet-Camoit, Bui, Pierre, Chevallier, Marchand, Coumoul, Garlatti, Andreau, Barouki, Aggerbeck: "2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 115, Issue 2, pp. 501-12, (2010) (PubMed).

Maslon, Hrstka, Vojtesek, Hupp: "A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin." dans: Journal of molecular biology, Vol. 404, Issue 3, pp. 418-38, (2010) (PubMed).

Zhao, Lee, Brown, Molloy, Marx, Pavlakis, Boyer, Stockler, Kaplan, Breit, Sutherland, Henshall, Horvath: "Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling." dans: Cancer research, Vol. 69, Issue 19, pp. 7696-703, (2009) (PubMed).

Détails sur AGR2

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Autre désignation: AGR2 (AGR2 Produits)

Synonymes: anticorps AG2, anticorps GOB-4, anticorps HAG-2, anticorps PDIA17, anticorps XAG-2, anticorps Agr2h, anticorps Gob-4, anticorps mAG-2, anticorps wu:fj29g05, anticorps zgc:112187, anticorps agr2, anticorps hag3, anticorps hag-3, anticorps bcmp11, anticorps MGC89004, anticorps XAgr2, anticorps agr2-A, anticorps anterior gradient 2, protein disulphide isomerase family member, anticorps anterior gradient 2, anticorps anterior gradient 3, protein disulphide isomerase family member, anticorps anterior gradient 2, protein disulphide isomerase family member S homeolog, anticorps AGR2, anticorps Agr2, anticorps agr2, anticorps agr3, anticorps agr2.S

Sujet: Full Gene Name: anterior gradient homolog 2 (Xenopus laevis)
Synonyms: AG2,GOB-4,HAG-2,XAG-2

ID gène: 10551