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Calpastatin anticorps (AA 275-310)

CAST Reactivité: Humain WB, IHC (p), FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5647087
  • Antigène Voir toutes Calpastatin (CAST) Anticorps
    Calpastatin (CAST)
    Épitope
    • 15
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 275-310
    Reactivité
    • 51
    • 21
    • 5
    • 2
    Humain
    Hôte
    • 41
    • 12
    Lapin
    Clonalité
    • 44
    • 9
    Polyclonal
    Conjugué
    • 27
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Calpastatin est non-conjugé
    Application
    • 38
    • 15
    • 13
    • 13
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    Antigen affinity purified
    Immunogène
    Amino acids 275-310 (QEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLR-human) were used as the immunogen for the Calpastatin antibody.
    Isotype
    IgG
    Top Product
    Discover our top product CAST Anticorps primaire
  • Indications d'application
    Optimal dilution of the Calpastatin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells,Immunohistochemistry (FFPE): 1-2 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the Calpastatin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    Calpastatin (CAST)
    Autre désignation
    Calpastatin (CAST Produits)
    Synonymes
    anticorps BS-17, anticorps calp3, anticorps CAST, anticorps sb:cb966, anticorps zgc:194249, anticorps cast, anticorps DKFZp469E0716, anticorps calpastatin, anticorps calpastatin S homeolog, anticorps Calpastatin, anticorps CAST, anticorps Cast, anticorps cast.S, anticorps cast, anticorps VDBG_09182, anticorps ical
    Sujet
    Calpastatin is a protein that in humans is encoded by the CAST gene. It is mapped to 5q15. The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
    UniProt
    P20810
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