MXD1 anticorps
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- Antigène Voir toutes MXD1 Anticorps
- MXD1 (MAX Dimerization Protein 1 (MXD1))
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MXD1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée (Details)
- Expected species reactivity: Human
- Purification
- Antigen affinity purified
- Immunogène
- A recombinant human protein corresponding to amino acids M1-L221 was used as the immunogen for the MAD antibody.
- Isotype
- IgG
- Top Product
- Discover our top product MXD1 Anticorps primaire
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- Indications d'application
- Optimal dilution of the MAD antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the MAD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- MXD1 (MAX Dimerization Protein 1 (MXD1))
- Autre désignation
- MAD / MXD1 / Max dimerization protein 1 (MXD1 Produits)
- Synonymes
- anticorps MXD1, anticorps si:dkey-202n14.4, anticorps xmad1, anticorps BHLHC58, anticorps MAD, anticorps MAD1, anticorps AW122478, anticorps Mad, anticorps Mad1, anticorps Mad-1, anticorps MAX dimerization protein 1, anticorps MAX dimerization protein 1 L homeolog, anticorps max dimerization protein 1, anticorps MXD1, anticorps mxd1, anticorps mxd1.L, anticorps Mxd1
- Sujet
- MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UniProt
- Q05195
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