PNP anticorps (AA 161-189)

N° du produit ABIN5647213

Détail du produit anti-PNP anticorps

Antigène: PNP (NP) (Nucleoside Phosphorylase (NP))

Épitope: AA 161-189

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNP est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: Amino acids 161-189 (AMSDAYDRTMRQRALSTWKQMGEQRELQE-human) were used as the immunogen for the Purine nucleoside phosphorylase antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Purine nucleoside phosphorylase antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Flow cytometry: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Purine nucleoside phosphorylase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur PNP

Antigène: PNP (NP) (Nucleoside Phosphorylase (NP))

Autre désignation: PNP / Purine Nucleoside Phosphorylase (NP Produits)

Synonymes: anticorps NP, anticorps PRO1837, anticorps PUNP, anticorps Np, anticorps AL024301, anticorps AU015798, anticorps Np-1, anticorps Np-2, anticorps Pnp1, anticorps purine nucleoside phosphorylase, anticorps purine-nucleoside phosphorylase, anticorps PNP, anticorps Pnp

Classe de substances: Viral Protein

Sujet: The PNP gene encodes Purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

UniProt: P00491

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus